« Back
Home /
CHIMAERIC Human IgE ANTI NP Antibody

CHIMAERIC Human IgE ANTI NP Antibody

Item no.	OASA00004
Manufacturer	AVIVA Systems Biology
Amount	2 ml
Category	Antibodies ELISA Primary Antibodies Immunostaining Functional Assays
Type	Antibody Monoclonal
Format	Liquid
Applications	ELISA, FA
Clone	JW8/1
Specific against	Human (Homo sapiens)
Host	Human
Isotype	IgE
Citations	1. Neuberger, M. S. et al. (1984) Recombinant antibodies possessing novel effector functions. Nature 312: 604-608. 2. Neuberger, M. S. et al. (1985) Making novel antibodies by expressing transfected immunoglobulin genes. TIBS 347-349. 3. Neuberger, M. S. et al. (1985) A hapten-specific chimaeric IgE antibody with Human physiological effector function. Naure 314: 268-270. 4. Neuberger, M. S. et al. (1986) Construction of novel antibodies by use of DNA transfection: design of plasmid vectors. Phil. Trans. R. Soc. Lond. A317: 425-432. 5. Sayers, I. et al. (2004) The importance of Lys-352 of human immunoglobulin E in FcepsilonRII/CD23 recognition. J Biol Chem. 279: 35320-5.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	N/A
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	ELISA: 1/20 - 1/100FN: This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays.
Product format	Liquid. None present
Reconstitution and storage	-20°C
Description of target	CHIMAERIC HUMAN IgE ANTI NP
Protein name	Ig epsilon chain C region
Clonality	Monoclonal
Purification	Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum
Immunogen	Hapten, 4-hydroxy-3-nitrophenylacetyl (NP).
Homology	Human
Manufacturer - Specificity	The immunoglobulin heavy chain has been produced by the linking of the antigen-binding, variable region genes of a mouse hybridoma to human constant region genes by in vitro DNA recombination procedures. The resulting chimeric antibody is subsequently expressed by the myeloma cell-line J558L after transfection. (The J558L cell-line self secretes a lambda light chain but no heavy chain). Thus a chimeric human IgE antibody specific for NP has been produced.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OASA00004-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 2 ml

available

Delivery expected until 11/13/2025

Express Delivery: Save 7 days

Compare

Add to wishlist

Get an offer