Human CD49f Antibody : PE

Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies

Wet Ice

ITGA6

Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

NP_000201.2

Monoclonal

CD49f