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SMARCA4 Antibody

ArtNr OAAB20952
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IP, ICC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Citations Khavari P.A.,et al.Nature 366:170-174(1993).
Khavari P.A.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
Chiba H.,et al.Nucleic Acids Res. 22:1815-1820(1994).
Wong A.K.C.,et al.Cancer Res. 60:6171-6177(2000).
Medina P.P.,et al.Hum. Mutat. 29:617-622(2008).
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias BRG1,CSS4,SNF2,SWI2,MRD16,RTPS2,BAF190,SNF2L4,SNF2LB,hSNF2b,BAF190A,SNF2-beta
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
185 kDa
Manufacturer - Application Additional Information
WB: 1:1000
ICC: 1:50
IP: 1:500
Gene symbol
SMARCA4
Gene Fullname
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Product format
Liquid
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Nucleotide accession_num
NM_001128844.1
Protein accession_num
NP_001122316.1
Clonality
Monoclonal
Homology
Human, Mouse
Formulation
Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 30.10.2025 

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