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SMARCA4 Antibody

SMARCA4 Antibody

Item no.	OAAB20952
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies By Organ Bladder Cancer Colorectal Cancer Breast Cancer Head & Neck Cancer Testicular & Prostate Cancer Gastric Cancer Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Khavari P.A.,et al.Nature 366:170-174(1993). Khavari P.A.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases. Chiba H.,et al.Nucleic Acids Res. 22:1815-1820(1994). Wong A.K.C.,et al.Cancer Res. 60:6171-6177(2000). Medina P.P.,et al.Hum. Mutat. 29:617-622(2008).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BRG1,CSS4,SNF2,SWI2,MRD16,RTPS2,BAF190,SNF2L4,SNF2LB,hSNF2b,BAF190A,SNF2-beta
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	185 kDa
Manufacturer - Application Additional Information	WB: 1:1000 ICC: 1:50 IP: 1:500
Gene symbol	SMARCA4
Gene Fullname	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Product format	Liquid
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Nucleotide accession_num	NM_001128844.1
Protein accession_num	NP_001122316.1
Clonality	Monoclonal
Homology	Human, Mouse
Formulation	Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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