Androgen Receptor Antibody (Phospho-Ser650)

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin

Wet Ice

IHC: 1:50~1:100
ELISA: 1:20000

androgen receptor

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849). Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Polyclonal

The antiserum was produced against synthesized peptide derived from human Androgen Receptor around the phosphorylation site of Ser650.

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.