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NLRP4 Antibody (OABF01758-100UL)

ArtNr OABF01758
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Horse (Equine), Pig (Porcine, Sus scrofa domesticus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias cancer/testis antigen 58;CLR19.5;CT58;NACHT,leucine rich repeat and PYD containing 4;NACHT,LRR and PYD domains-containing protein 4;NALP4;nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 4;PAAD and NACHT-containing protein 2;PAN2;PYPAF4;PYRIN and NACHT-containing protein 2;PYRIN-containing APAF1-like protein 4;ribonuclease inhibitor 2;RNH2.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Species Tested
Human, Rat
Manufacturer - Application Additional Information
ELISA: 1:500~1000IHC-P: 1:200~400IHC-F: 1:100~500Fluorescent (IHC-P): 1:50~200Fluorescent (IHC-F): 1:50~200Fluorescent-ICC: 1:50~200
Gene symbol
NLRP4
Gene Fullname
NLR family pyrin domain containing 4
Product format
Liquid Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution and storage
-20°C
Description of target
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
Protein name
NACHT, LRR and PYD domains-containing protein 4
Clonality
Polyclonal
Purification
Protein A Purified
Immunogen
KLH conjugated synthetic peptide derived from human NALP4
Manufacturer - Specificity
This antibody will detect multiple forms of NALP4, including the A, C and E Mouse variants.
Concentration
1 ug/ul

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

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