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NLRP4 Antibody (OABF01758-100UL)

NLRP4 Antibody (OABF01758-100UL)

Item no.	OABF01758
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Horse (Equine), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cancer/testis antigen 58;CLR19.5;CT58;NACHT,leucine rich repeat and PYD containing 4;NACHT,LRR and PYD domains-containing protein 4;NALP4;nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 4;PAAD and NACHT-containing protein 2;PAN2;PYPAF4;PYRIN and NACHT-containing protein 2;PYRIN-containing APAF1-like protein 4;ribonuclease inhibitor 2;RNH2.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry-Frozen\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Species Tested	Human, Rat
Manufacturer - Application Additional Information	ELISA: 1:500~1000IHC-P: 1:200~400IHC-F: 1:100~500Fluorescent (IHC-P): 1:50~200Fluorescent (IHC-F): 1:50~200Fluorescent-ICC: 1:50~200
Gene symbol	NLRP4
Gene Fullname	NLR family pyrin domain containing 4
Product format	Liquid Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution and storage	-20°C
Description of target	May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
Protein name	NACHT, LRR and PYD domains-containing protein 4
Clonality	Polyclonal
Purification	Protein A Purified
Immunogen	KLH conjugated synthetic peptide derived from human NALP4
Manufacturer - Specificity	This antibody will detect multiple forms of NALP4, including the A, C and E Mouse variants.
Concentration	1 ug/ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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