GDF15 Antibody

ArtNr	OACA02491
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Testicular & Prostate Cancer Immunostaining Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GDF-15;growth/differentiation factor 15;macrophage inhibitory cytokine 1;MIC1;MIC-1;NAG-1;non-steroidal anti-inflammatory drug-activated gene-1;NRG-1;NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;PDF;PLAB;placental bone morphogenetic protein;placental TGF-beta;prostate differentiation factor;PTGFB;PTGF-beta.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GDF15
Gene Fullname	growth differentiation factor 15
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).
Nucleotide accession_num	NM_004864
Protein accession_num	NP_004855
Protein name	Growth/differentiation factor 15
Clonality	Monoclonal
Purification	Protein G Purified
Immunogen	Recombinant GDF15 Protein
Manufacturer - Specificity	Specific for Human GDF15 denatured and native forms
Formulation	0.01M PBS, PH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OACA02491-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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