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GDF15 Antibody

GDF15 Antibody

Item no.	OACA02491
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Testicular & Prostate Cancer Immunostaining Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Monoclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GDF-15;growth/differentiation factor 15;macrophage inhibitory cytokine 1;MIC1;MIC-1;NAG-1;non-steroidal anti-inflammatory drug-activated gene-1;NRG-1;NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;PDF;PLAB;placental bone morphogenetic protein;placental TGF-beta;prostate differentiation factor;PTGFB;PTGF-beta.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GDF15
Gene Fullname	growth differentiation factor 15
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).
Nucleotide accession_num	NM_004864
Protein accession_num	NP_004855
Protein name	Growth/differentiation factor 15
Clonality	Monoclonal
Purification	Protein G Purified
Immunogen	Recombinant GDF15 Protein
Manufacturer - Specificity	Specific for Human GDF15 denatured and native forms
Formulation	0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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