ZBTB48 Antibody

ArtNr	OACA08410
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Mesothelioma Immunohistochemistry Western Blot ELISA Senescence Primary Antibodies By Organ Lung Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GLI-Kruppel family member HKR3;HKR3;krueppel-related zinc finger protein 3;pp9964;telomere zinc finger-associated protein;telomeric zinc finger-associated protein;TZAP;zinc finger and BTB domain-containing protein 48;zinc finger protein 855;ZNF855.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ZBTB48
Gene Fullname	zinc finger and BTB domain containing 48
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).
Nucleotide accession_num	NM_001278647
Protein accession_num	NP_001265576
Protein name	Telomere zinc finger-associated protein
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Telomere zinc finger-associated protein (1-280AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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Menge: 50 ul

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Lieferung vsl. bis 25.12.2025

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