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ZBTB48 Antibody

ZBTB48 Antibody

Item no.	OACA08410
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Mesothelioma Immunohistochemistry Western Blot ELISA Senescence Primary Antibodies By Organ Lung Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GLI-Kruppel family member HKR3;HKR3;krueppel-related zinc finger protein 3;pp9964;telomere zinc finger-associated protein;telomeric zinc finger-associated protein;TZAP;zinc finger and BTB domain-containing protein 48;zinc finger protein 855;ZNF855.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ZBTB48
Gene Fullname	zinc finger and BTB domain containing 48
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).
Nucleotide accession_num	NM_001278647
Protein accession_num	NP_001265576
Protein name	Telomere zinc finger-associated protein
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Telomere zinc finger-associated protein (1-280AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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