MYLIP Antibody

ArtNr	OACA08781
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Obesity Immunohistochemistry ELISA Lipoprotein Receptors & Associated Proteins Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	band 4.1 superfamily member BZF1;cellular modulator of immune recognition (c-MIR);E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor;E3 ubiquitin-protein ligase MYLIP;IDOL;inducible degrader of the LDL-receptor;MIR;Myosin regulatory light chain interacting protein;RING-type E3 ubiquitin transferase MYLIP.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	IHC: 1:20~200
Gene symbol	MYLIP
Gene Fullname	myosin regulatory light chain interacting protein
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Nucleotide accession_num	NM_013262
Protein accession_num	NP_037394
Protein name	E3 ubiquitin-protein ligase MYLIP
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
Formulation	PBS with, 50% glycerol, pH7.3.
Concentration	Varies by lot. See vial for concentration.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

OACA08781-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 50 ul

lieferbar

Lieferung vsl. bis 30.10.2025

Express-Lieferung: 1 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern