DNAJC3 Antibody

ArtNr	OACA09545
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACPHD;DnaJ (Hsp40) homolog,subfamily C,member 3;dnaJ homolog subfamily C member 3;endoplasmic reticulum DNA J domain-containing protein 6;ERdj6;ER-resident protein ERdj6;HP58;interferon-induced,double-stranded RNA-activated protein kinase inhibitor;P58;p58(IPK);P58IPK;PRKRI;protein kinase inhibitor of 58 kDa;protein kinase inhibitor p58;protein-kinase,interferon-inducible double stranded RNA dependent inhibitor.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DNAJC3
Gene Fullname	DnaJ heat shock protein family (Hsp40) member C3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Nucleotide accession_num	NM_006260
Protein accession_num	NP_006251
Protein name	DnaJ homolog subfamily C member 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human DnaJ homolog subfamily C member 3 protein (277-496AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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