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DNAJC3 Antibody

DNAJC3 Antibody

Item no.	OACA09545
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACPHD;DnaJ (Hsp40) homolog,subfamily C,member 3;dnaJ homolog subfamily C member 3;endoplasmic reticulum DNA J domain-containing protein 6;ERdj6;ER-resident protein ERdj6;HP58;interferon-induced,double-stranded RNA-activated protein kinase inhibitor;P58;p58(IPK);P58IPK;PRKRI;protein kinase inhibitor of 58 kDa;protein kinase inhibitor p58;protein-kinase,interferon-inducible double stranded RNA dependent inhibitor.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DNAJC3
Gene Fullname	DnaJ heat shock protein family (Hsp40) member C3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Nucleotide accession_num	NM_006260
Protein accession_num	NP_006251
Protein name	DnaJ homolog subfamily C member 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human DnaJ homolog subfamily C member 3 protein (277-496AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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