KAT2B Antibody

ArtNr	OACA09633
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CAF;CREBBP-associated factor;histone acetylase PCAF;histone acetyltransferase KAT2B;histone acetyltransferase PCAF;K(lysine) acetyltransferase 2B;Lysine acetyltransferase 2B;P/CAF;p300/CBP-associated factor;PCAF;spermidine acetyltransferase KAT2B.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	KAT2B
Gene Fullname	lysine acetyltransferase 2B
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY, PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5 (PubMed:29174768). Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4 (PubMed:27796307).
Nucleotide accession_num	NM_003884
Protein accession_num	NP_003875
Protein name	Histone acetyltransferase KAT2B
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Histone acetyltransferase KAT2B protein (767-832AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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