PIM3 Antibody

ArtNr	OACA10087
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Bladder Cancer Thyroid Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	pim-3;pim-3 oncogene;serine/threonine kinase Pim-3;serine/threonine-protein kinase pim-3.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PIM3
Gene Fullname	Pim-3 proto-oncogene, serine/threonine kinase
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
Nucleotide accession_num	NM_001001852
Protein accession_num	NP_001001852
Protein name	Serine/threonine-protein kinase pim-3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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OACA10087-datasheet.pdf

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Menge: 50 ug

lieferbar

Lieferung vsl. bis 30.10.2025

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