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PIM3 Antibody

PIM3 Antibody

Item no.	OACA10087
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Bladder Cancer Thyroid Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	pim-3;pim-3 oncogene;serine/threonine kinase Pim-3;serine/threonine-protein kinase pim-3.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PIM3
Gene Fullname	Pim-3 proto-oncogene, serine/threonine kinase
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
Nucleotide accession_num	NM_001001852
Protein accession_num	NP_001001852
Protein name	Serine/threonine-protein kinase pim-3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/30/2025

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