CILP Antibody

ArtNr	OACD02536
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Blastoma Carcinoma Sarcoma Cell Biology Cell Culture Cytokines Mesothelioma Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Endocrine Regulation of Lipid Metabolism Primary Antibodies By Organ Colorectal Cancer Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	132 kDa
Manufacturer - Application Additional Information	WB: 0.5-2 ug/mLIHC: 5-20 ug/mLICC: 5-20 ug/mL
Gene symbol	Cilp
Gene Fullname	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).
Nucleotide accession_num	NM_173385
Protein accession_num	NP_775561.1
Protein name	Cartilage intermediate layer protein 1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Recombinant CILP (Pro604~His864) expressed in E.coli
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against CILP. It has been selected for its ability to recognize CILP in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.45 mg/ml

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OACD02536-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 30.10.2025

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