Comparison

CILP Antibody

Item no. OACD02536
Manufacturer AVIVA Systems Biology
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IP, IHC, ICC
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
132 kDa
Manufacturer - Application Additional Information
WB: 0.5-2 ug/mLIHC: 5-20 ug/mLICC: 5-20 ug/mL
Gene symbol
Cilp
Gene Fullname
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Product format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage
2°C to 8°C|-20°C
Description of target
Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).
Nucleotide accession_num
NM_173385
Protein accession_num
NP_775561.1
Protein name
Cartilage intermediate layer protein 1
Clonality
Polyclonal
Purification
Affinity Purified; Protein A Purified
Immunogen
Recombinant CILP (Pro604~His864) expressed in E.coli
Manufacturer - Specificity
The antibody is a rabbit polyclonal antibody raised against CILP. It has been selected for its ability to recognize CILP in immunohistochemical staining and western blotting.
Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration
0.45 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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