KEAP1 Antibody

ArtNr	OACD04962
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cytosolic inhibitor of Nrf2;IN;INRF2;kelch-like ECH-associated protein 1;mKIAA0132;NRF2 cytosolic inhibitor;ring canal protein.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 0.5-2 ug/mLIHC: 5-20 ug/mLICC: 5-20 ug/mL
Gene symbol	Keap1
Gene Fullname	kelch-like ECH-associated protein 1
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
Nucleotide accession_num	NM_001110305
Protein accession_num	NP_001103775.1
Protein name	Kelch-like ECH-associated protein 1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Recombinant KEAP1 (Met1~Gln286) expressed in E.coli
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against KEAP1. It has been selected for its ability to recognize KEAP1 in immunohistochemical staining and western blotting.
Concentration	1 mg/ml

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OACD04962-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 13.11.2025

Express-Lieferung: 13 Tage sparen

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