Comparison

KEAP1 Antibody

Item no. OACD04962
Manufacturer AVIVA Systems Biology
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IP, IHC, ICC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias cytosolic inhibitor of Nrf2;IN;INRF2;kelch-like ECH-associated protein 1;mKIAA0132;NRF2 cytosolic inhibitor;ring canal protein.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Manufacturer - Application Additional Information
WB: 0.5-2 ug/mLIHC: 5-20 ug/mLICC: 5-20 ug/mL
Gene symbol
Keap1
Gene Fullname
kelch-like ECH-associated protein 1
Product format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage
2°C to 8°C|-20°C
Description of target
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
Nucleotide accession_num
NM_001110305
Protein accession_num
NP_001103775.1
Protein name
Kelch-like ECH-associated protein 1
Clonality
Polyclonal
Purification
Affinity Purified; Protein A Purified
Immunogen
Recombinant KEAP1 (Met1~Gln286) expressed in E.coli
Manufacturer - Specificity
The antibody is a rabbit polyclonal antibody raised against KEAP1. It has been selected for its ability to recognize KEAP1 in immunohistochemical staining and western blotting.
Concentration
1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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