IL-1beta Antibody

ArtNr	OADB00342
Hersteller	AVIVA Systems Biology
Menge	500 ug
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Cell Status Apoptosis Flow Cytometry Blocking Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	FC, Blocking
Clon	B-A15
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	ChÃªne L. et al., J. Virol., 1999; 73 : 2064 - 2073 Ikoma, Y. et al., Mol Hum Reprod.,2003; 9(2): 103-10.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	IL-1,IL1F2,IL1beta,IL1-BETA
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Mouse IgG1
Shipping Temperature	Wet Ice
Molecular Weight	31 kDa
Gene symbol	IL-1beta
Gene Fullname	interleukin 1 beta
Product format	Lyophilized
Reconstitution and storage	Store at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Nucleotide accession_num	NM_000576.2
Protein accession_num	NP_000567.1
Protein name	interleukin-1 beta
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises both natural (pro and mature) and recombinant human IL-1b
Biological activity	Blocks IL-1b induced proliferation on D10S murine cell line
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

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OADB00342-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 25.12.2025

Express-Lieferung: 1 Tage sparen

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