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IL-1beta Antibody

IL-1beta Antibody

Item no.	OADB00342
Manufacturer	AVIVA Systems Biology
Amount	500 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Cell Status Apoptosis Flow Cytometry Blocking Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized
Applications	FC, Blocking
Clone	B-A15
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	ChÃªne L. et al., J. Virol., 1999; 73 : 2064 - 2073 Ikoma, Y. et al., Mol Hum Reprod.,2003; 9(2): 103-10.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	IL-1,IL1F2,IL1beta,IL1-BETA
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Mouse IgG1
Shipping Temperature	Wet Ice
Molecular Weight	31 kDa
Gene symbol	IL-1beta
Gene Fullname	interleukin 1 beta
Product format	Lyophilized
Reconstitution and storage	Store at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Nucleotide accession_num	NM_000576.2
Protein accession_num	NP_000567.1
Protein name	interleukin-1 beta
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises both natural (pro and mature) and recombinant human IL-1b
Biological activity	Blocks IL-1b induced proliferation on D10S murine cell line
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 12/25/2025

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