EPCAM Antibody

ArtNr	OAEE00813
Hersteller	AVIVA Systems Biology
Menge	100 tests (T100)
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Obesity Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Lipid & Fatty Acid Transport Primary Antibodies By Organ Bladder Cancer
Typ	Antibody Monoclonal
Applikationen	FC
Clon	VU-1D9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	FITC
Citations	Brunner A, Prelog M, Verdorfer I, Tzankov A, Mikuz G, Ensinger C: EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J Clin Pathol. 2008 Mar;61(3):307-10. Winter MJ, Nagtegaal ID, van Krieken JH, Litvinov SV: The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology. Am J Pathol. 2003 Dec;163(6):2139-48. Li G, Passebosc-Faure K, Lambert C, Gentil-Perret A, Blanc F, Oosterwijk E, Mosnier JF, Genin C, Tostain J: Flow cytometric analysis of antigen expression in malignant and normal renal cells. Anticancer Res. 2000 Jul-Aug;20(4):2773-8. Ogura E, Senzaki H, Yoshizawa K, Hioki K, Tsubura A: Immunohistochemical localization of epithelial glycoprotein EGP-2 andcarcinoembryonic antigen in normal colonic mucosa and colorectal tumors. Anticancer Res. 1998 Sep-Oct;18(5B):3669-75. Tsubura A, Senzaki H, Sasaki M, Hilgers J, Morii S: Immunohistochemical demonstration of breast-derived and/or carcinoma-associatedglycoproteins in normal skin appendages and their tumors. J Cutan Pathol. 1992 Feb;19(1):73-9.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	adenocarcinoma-associated antigen;cell surface glycoprotein Trop-1;DIAR5;EGP-2;EGP314;EGP40;epithelial cell adhesion molecule;Epithelial cell surface antigen;Epithelial glycoprotein;epithelial glycoprotein 314;ESA;HNPCC8;human epithelial glycoprotein-2;KS 1/4 antigen;KS1/4;KSA;M4S1;major gastrointestinal tumor-associated protein GA733-2;membrane component,chromosome 4,surface marker (35kD glycoprotein);MIC18;MK-1;TACSTD1;TROP1;trophoblast cell surface antigen 1;tumor-associated calcium signal transducer 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	EPCAM
Gene Fullname	epithelial cell adhesion molecule
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Nucleotide accession_num	NM_002354.2
Protein accession_num	NP_002345.2
Protein name	Epithelial cell adhesion molecule
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Small cell lung carcinoma cell line H69.
Manufacturer - Specificity	The mouse monoclonal antibody VU-1D9 recognizes an epitope within EGF-like domain I of CD326 / EpCAM, a marker of epithelial lineages. This antibody strongly stains various normal epithelial cells and carcinomas.
Formulation	FITC
Concentration	20 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

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Menge: 100 tests (T100)

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Lieferung vsl. bis 08.01.2026

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