LMNA Antibody

ArtNr	OAGA08378
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IP, ICC
Clon	GT9712
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	FPL,IDC,LFP,CDDC,EMD2,FPLD,HGPS,LDP1,LMN1,LMNC,MADA,PRO1,CDCD1,CMD1A,FPLD2,LMNL1,CMT2B1,LGMD1B
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IP: 1:100-1:500, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	LMNA
Gene Fullname	lamin A/C
Product format	Liquid
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Nucleotide accession_num	NM_001257374.2
Protein accession_num	NP_001244303.1
Protein name	lamin
Clonality	Monoclonal
Purification	Affinity purified by Protein G.
Immunogen	Recombinant protein encompassing a sequence within the center region of human Lamin A/C. The exact sequence is proprietary.
Concentration	1 mg/ml
Storage Buffer	PBS

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OAGA08378-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 08.01.2026

Express-Lieferung: 1 Tage sparen

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