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IGF1R Antibody (Phospho-Tyr1161)

IGF1R Antibody (Phospho-Tyr1161)

ArtNr	OASG03735
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Melanoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IGFR,CD221,IGFIR,JTK13
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Manufacturer - Targets	Phospho-Tyr1161
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 1:500~2000IHC: 1:100~300IF: 1:200~1000ELISA: 1:40000
Gene symbol	IGF1R, INSR
Gene Fullname	insulin-like growth factor 1 receptor
Protein size	1100-1180aa
Product format	Liquid PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and storage	Store at -20°C for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
Description of target	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit anti-serum by affinity-chromatograhy.
Immunogen	Synthesized phospho-peptide around the phosphorylation site of human IGF-IR (phospho Tyr1161)
Manufacturer - Specificity	Phospho-IGF-IR-Tyr1161 polyclonal antibody (Insulin-like growth factor 1 receptor and Insulin receptor) binds to endogenous Insulin-like growth factor 1 receptor and Insulin receptor at the amino acid region 1100-1180 only when phosphorylated at Tyr1
Concentration	1 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OASG03735-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 30.10.2025

Express-Lieferung: 1 Tage sparen

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