|
Hersteller |
Raybiotech
|
|
Kategorie |
|
|
Typ |
Proteins |
|
Specific against |
Human |
|
Menge |
10 ug |
|
ArtNr |
229-20197 |
|
eClass 6.1 |
34160400 |
|
eClass 9.0 |
42020190 |
|
Lieferbar |
 |
| Short Description |
Purified recombinant IL-22 expressed in E.coli |
| Introduction |
Interleukin-22 (IL-22) is a regulatory cytokine and member of the IL-10 family, secreted by activated T cells, which signals through a class II cytokine receptor system consisting of IL-22R and IL-10R-beta/CRF2-4.
IL-22 has been shown to act as an inhibitor of the production of IL-4 by Th2 cells, up-regulate the production of acute phase reactants in the pancreas and liver, and to be up-regulated in intestinal inflammation associated with Crohn’s disease. |
| Protein Name |
IL-22 |
| Molecular Weight (kDa) |
33.6kD (146 amino acid homodimer) |
| Purity |
>98% by SDS PAGE and HPLC analysis |
| Concentration |
ca.0.1mg/ml |
| Preservative |
None present |
| Endotoxin Level |
<1EU/ug |
| Protein Type |
Recombinant Protein |
| Recommended Applications |
Functional Assays |
| Biological activity |
Determined by its ability to activate STAT following receptor ligand interaction. |
| Reconstitution |
Reconstitute with 100ul distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution. |
| Storage/stability |
Prior to reconstitution store at +4° C.
After reconstitution store at -20° C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution. |
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