MAP3K9/MAP3K10 Antibody (Phospho-Thr312/266)

ArtNr	OASG04568
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry Senescence Primary Antibodies By Organ Bladder Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MLK1,MEKK9,PRKE1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Manufacturer - Targets	Phospho-Thr312/266
Shipping Temperature	Wet Ice
Molecular Weight	120 kDa
Manufacturer - Application Additional Information	IHC: 1:100-1:300 ELISA: 1:5000;
Gene symbol	MAP3K10, MAP3K9
Gene Fullname	mitogen-activated protein kinase kinase kinase 9
Product format	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and storage	Store at -20C. Avoid repeated freeze/thaw cycles.
Description of target	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Synthesized peptide derived from human MLK1/2 around the phosphorylation site of T312/266. Region: 250-330aa.
Manufacturer - Specificity	Phospho-MLK1/2 (T312/266) Polyclonal Antibody detects endogenous levels of MLK1/2 protein only when phosphorylated at T312/266.
Concentration	1 mg/ml

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Menge: 100 ul

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Lieferung vsl. bis 30.10.2025

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