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PTBP1 Recombinant Protein

PTBP1 Recombinant Protein

ArtNr	OPCD00681
Hersteller	AVIVA Systems Biology
Menge	10 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Typ	Proteins Recombinant
Applikationen	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Unconjugated; HIS
Purity	> 90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	57 kDa RNA-binding protein PPTB-1;heterogeneous nuclear ribonucleoprotein I;heterogeneous nuclear ribonucleoprotein polypeptide I;hnRNP I;HNRNPI;HNRNP-I;HNRPI;polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I);polypyrimidine tract-binding protein 1;pPTB;PTB;PTB-1;PTB2;PTB3;PTB4;PTB-T;RNA-binding protein.
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Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	61kDa
Gene symbol	PTBP1
Gene Fullname	polypyrimidine tract binding protein 1
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Nucleotide accession_num	NM_002819.4
Protein accession_num	NP_002810.1
Protein name	Polypyrimidine tract-binding protein 1
Concentration	200 ug/mL (prior to lyoph)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OPCD00681-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 25.12.2025

Express-Lieferung: 1 Tage sparen

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