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MMP1 Recombinant Protein (Human)

MMP1 Recombinant Protein (Human)

ArtNr	OPED00090
Hersteller	AVIVA Systems Biology
Menge	10 ug
Kategorie	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Stainings ECM
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	>95% (SDS-PAGE)
Dry ice	Yes
Citations	Enzymatic, physicochemical and biological properties of MMP-sensitive alginate hydrogels: K.B. Fonseca, et al.; Soft Matter 9, 3283 (2013), Development and validation of novel enzyme activity methods to assess inhibition of matrix metalloproteinases (MMPs) in human serum by antibodies against enzyme therapeutics: T.J. Edkins, et al.; J. Pharm. Biomed. Anal. 70, 408 (2012), Abstract; Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines: A. Jabaiah, et al.; Chem. Biol. 18, 392 (2011), Abstract; Full Text Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors: M. Gooyit, et al.; Chem. Biol. Drug Des. 74, 535 (2009), Abstract;
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CLG;CLGN;fibroblast collagenase;interstitial collagenase;matrix metallopeptidase 1 (interstitial collagenase);matrix metalloprotease 1;Matrix metalloproteinase-1.
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Dry Ice
Molecular Weight	20 kDa
Manufacturer - Application Additional Information	Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.
Gene symbol	MMP1
Gene Fullname	matrix metallopeptidase 1
Protein size	Recombinant
Product format	Liquid. In 50mM TRIS, pH 7.5, containing 5mM calcium chloride, 300mM sodium chloride, 20 uM zinc chloride, 0.5% Brij-35, and 30% glycerol.
Reconstitution and storage	Store at -80C
Description of target	Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369).
Nucleotide accession_num	NM_001190942.1
Protein accession_num	NP_001177871.1
Protein name	Interstitial collagenase
Purification	Purified by multi-step chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 10 ug

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Lieferung vsl. bis 25.12.2025

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