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SUMO4 Recombinant Protein (Human)

ArtNr OPED00135
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Purity >90% (SDS-PAGE)
Dry ice Yes
Citations A stress-dependent SUMO4 sumoylation of its substrate proteins: W. Wei, et al.; BBRC 375, 454 (2008), Abstract;
SUMO4 and its role in type 1 diabetes pathogenesis: C.Y. Wang & J.X. She; Diabetes Metab. Res. Rev. 24, 93 (2008), Abstract;
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress: D. Guo, et al.; BBRC 337, 1308 (2005), Abstract;
SUMO, ubiquitin's mysterious cousin: S. Muller, et al.; Nat. Rev. Mol. Cell Biol. 2, 202 (2001), Abstract;
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias dJ281H8.4;IDDM5;insulin-dependent diabetes mellitus 5;small ubiquitin-like modifier 4 protein;Small ubiquitin-like protein 4;small ubiquitin-related modifier 4;SMT3 suppressor of mif two 3 homolog 2;SMT3 suppressor of mif two 3 homolog 4;SMT3H4;SUMO-4.
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Protein
Manufacturer - Category
Root Catalog/Products/Recombinant Proteins
Shipping Temperature
Dry Ice
Molecular Weight
13 kDa
Manufacturer - Application Additional Information
For use in SUMO-4 conjugation studies.
Gene symbol
SUMO4
Gene Fullname
small ubiquitin like modifier 4
Protein size
Recombinant
Product format
Liquid. In 20mM HEPES, pH 8.0, containing 1mM DTT.
Reconstitution and storage
Store at -80C
Description of target
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.
Nucleotide accession_num
NM_001002255.1
Protein accession_num
NP_001002255.1
Protein name
Small ubiquitin-related modifier 4
Purification
Purified by multistep chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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