Vergleich

Phospholipase A2 Protein (OPPA00392)

ArtNr OPPA00392
Hersteller AVIVA Systems Biology
Menge 100ug
Kategorie
Typ Proteins
Format 10mM Tris-HCl, pH 6.5, 0.1M Sodium Phosphate and 8M urea.
Applikationen WB, ELISA
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Allergen Api m I, Api m 1, Phospholipase A2, Phospholipase A2 P00630 Bee Venom Protein Recombinant
Similar products PA2-BVP
Lieferbar
Gene symbol
PA2-BVP
Protein name
Phospholipase A2
Product format
Liquid. Supplied in 20mM Tris-HCl, pH 7.2, 1.5M urea and 50% glycerol.
Gene id
406141
Reconstitution and storage
Phospholipase A2 although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.
Description of target
Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14 - 16-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
Purification
Purified by proprietary chromatographic technique.
Purity
Protein is >90% pure as determined by 10% SDS-PAGE.
Drywet
Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ug
Lieferbar: In stock
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