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Phospholipase A2 Protein (OPPA00392)

Phospholipase A2 Protein (OPPA00392)

Item no.	OPPA00392
Manufacturer	AVIVA Systems Biology
Amount	100ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Western Blot ELISA Cardiovascular Research Thrombosis & Hemostasis Enzymes Fatty Acid Catabolism
Type	Proteins
Format	10mM Tris-HCl, pH 6.5, 0.1M Sodium Phosphate and 8M urea.
Applications	WB, ELISA
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Allergen Api m I, Api m 1, Phospholipase A2, Phospholipase A2 P00630 Bee Venom Protein Recombinant
Similar products	PA2-BVP
Available
Gene symbol	PA2-BVP
Protein name	Phospholipase A2
Product format	Liquid. Supplied in 20mM Tris-HCl, pH 7.2, 1.5M urea and 50% glycerol.
Gene id	406141
Reconstitution and storage	Phospholipase A2 although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.
Description of target	Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14 - 16-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
Purification	Purified by proprietary chromatographic technique.
Purity	Protein is >90% pure as determined by 10% SDS-PAGE.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPPA00392-datasheet.pdf

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Amount: 100ug

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Delivery expected until 9/25/2025

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