tPA Protein

ArtNr	OPPA00785
Hersteller	AVIVA Systems Biology
Menge	20 ug
Kategorie	Oncology Food Safety Proteins Peptides & Proteins Recombinant Proteins By Organ Breast Cancer
Typ	Proteins Recombinant
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	Hamster - Armenian
Purity	Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TPA,T-PA
Similar products	tPA
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Room Temperature
Molecular Weight	59 kDa
Gene symbol	TPA
Protein size	Recombinant
Product format	Lyophilized Each mg of tPA contains 1.7 grams L-arginine, 0.5 g phosphoric acid and 4 mg tween 80 Physical Appearance: Sterile filtered white freeze-dried powder
Reconstitution and storage	It is recommended to reconstitute the lyophilized tPA in sterile 18M-omega-cm H₂O not less than 100 ug/mL, which can then be further diluted to other aqueous solutions. Lyophilized tPA, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, tPA should be stored at 4°C between 2-7 days and for further use below -18°C. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze/thaw cycles.
Description of target	Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine protease which converts plasminogen into plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism. Tissue Plasminogen Activator Human Recombinant produced in CHO cells is a single, glycosylated polypeptide chain containing 527 amino acids.
Protein accession_num	NP_000921.1
Protein name	Tissue-type plasminogen activator
Purification	Purified by proprietary chromatographic techniques.
Biological activity	Enzymatic Activity: 580, 000 IU/mg.

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OPPA00785-datasheet.pdf

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Menge: 20 ug

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Lieferung vsl. bis 30.10.2025

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