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tPA Protein

tPA Protein

Item no.	OPPA00785
Manufacturer	AVIVA Systems Biology
Amount	20 ug
Category	Oncology Food Safety Proteins Peptides & Proteins Recombinant Proteins By Organ Breast Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	Hamster - Armenian
Purity	Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TPA,T-PA
Similar products	tPA
Shipping Condition	Room temperature
Available
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Room Temperature
Molecular Weight	59 kDa
Gene symbol	TPA
Protein size	Recombinant
Product format	Lyophilized Each mg of tPA contains 1.7 grams L-arginine, 0.5 g phosphoric acid and 4 mg tween 80 Physical Appearance: Sterile filtered white freeze-dried powder
Reconstitution and storage	It is recommended to reconstitute the lyophilized tPA in sterile 18M-omega-cm H₂O not less than 100 ug/mL, which can then be further diluted to other aqueous solutions. Lyophilized tPA, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, tPA should be stored at 4°C between 2-7 days and for further use below -18°C. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze/thaw cycles.
Description of target	Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine protease which converts plasminogen into plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism. Tissue Plasminogen Activator Human Recombinant produced in CHO cells is a single, glycosylated polypeptide chain containing 527 amino acids.
Protein accession_num	NP_000921.1
Protein name	Tissue-type plasminogen activator
Purification	Purified by proprietary chromatographic techniques.
Biological activity	Enzymatic Activity: 580, 000 IU/mg.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 10/30/2025

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