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Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

ArtNr	03611-25-50
Hersteller	BioGems
Menge	50 ug
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Neural Adhesion Molecules Antibodies By Cell Type Carcinoma Flow Cytometry Primary Antibodies By Organ Skin Cancer
Typ	Antibody
Format	SAFIRE Purified
Applikationen	FC
Clon	23C6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Horton, M. A., Lewis, D., McNulty, K., Pringle, J. A., & Chambers, T. J. (1985). Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer research, 45(11 Part 2), 5663-5669. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Chuntharapai, A., Bodary, S., Horton, M., & Kim, K. J. (1993). Blocking monoclonal antibodies to αvβ3 integrin: A unique epitope of αvβ3 integrin is present on human osteoclasts. Experimental cell research, 205(2), 345-352.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 23C6 monoclonal antibody specifically reacts with the human CD51/61 molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity, Angiogenesis
Format	SAFIRE Purified

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03611-25-50-datasheet.pdf

03611-25-50-safety-datasheet.pdf