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Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

Anti-Human CD51/CD61 (Integrin alpha v beta 3) SAFIRE Purified

Item no.	03611-25-50
Manufacturer	BioGems
Amount	50 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Neural Adhesion Molecules Antibodies By Cell Type Carcinoma Flow Cytometry Primary Antibodies By Organ Skin Cancer
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	23C6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Horton, M. A., Lewis, D., McNulty, K., Pringle, J. A., & Chambers, T. J. (1985). Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer research, 45(11 Part 2), 5663-5669. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Chuntharapai, A., Bodary, S., Horton, M., & Kim, K. J. (1993). Blocking monoclonal antibodies to αvβ3 integrin: A unique epitope of αvβ3 integrin is present on human osteoclasts. Experimental cell research, 205(2), 345-352.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 23C6 monoclonal antibody specifically reacts with the human CD51/61 molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity, Angiogenesis
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

03611-25-50-datasheet.pdf

03611-25-50-safety-datasheet.pdf