« Zurück
Startseite /
Anti-Human CD180 (RP-105) SAFIRE Purified

Anti-Human CD180 (RP-105) SAFIRE Purified

ArtNr	12911-25-100
Hersteller	BioGems
Menge	100 ug
Kategorie	Oncology Food Safety Drugs Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Format	SAFIRE (Functional)
Applikationen	FC
Clon	MHR73-11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Miura, Y., Shimazu, R., Miyake, K., Akashi, S., Ogata, H., Yamashita, Y., ... & Kimoto, M. (1998). RP105 is associated with MD-1 and transmits an activation signal in human B cells. Blood, 92(8), 2815-2822. Miguet, L., Lennon, S., Baseggio, L., Traverse-Glehen, A., Berger, F., Perrusson, N., ... & Mauvieux, L. (2013). Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas. Leukemia, 27(8), 1748-1750. Koarada, S., Tada, Y., Sohma, Y., Haruta, Y., Suematsu, R., Mitamura, M., ... & Nagasawa, K. (2010). Autoantibody-producing RP105-B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects. Rheumatology, 49(4), 662-670.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The MHR73-11 monoclonal antibody binds to human CD180, a 105kDA cell surface molecule consisting of extracellular leucine rich repeats (LCC) and a short cytoplasmic tail also known as Bgp-95 and RP105. CD180 is expressed on B cells, dendritic cells, monocytes, and macrophages. It forms a cell surface receptor complex with MD-1 and with TLR4 is involved with the recognition of bacterial lipopolysaccharide (LPS). The MHR73-11 antibody is reported to protect against dexamethasone and irradiation induced apoptosis in B cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Innate Immunity, Apoptosis
Format	SAFIRE (Functional)

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

12911-25-100-datasheet.pdf

12911-25-100-safety-datasheet.pdf