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Anti-Mouse CD18 SAFIRE Purified

Anti-Mouse CD18 SAFIRE Purified

ArtNr	10212-25-50
Hersteller	BioGems
Menge	50 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies By Organ Skin Cancer
Typ	Antibody
Format	SAFIRE Purified
Applikationen	FC
Clon	M18/2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Citations	Driessens, M. H., Van Hulten, P., Zuurbier, A., La Riviere, G., & Roos, E. (1996). Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18. Evidence that the LFA-1 binding sites for ICAM-1,-2, and-3 are distinct. Journal of leukocyte biology, 60(6), 758-765. Zahalka, M. A., & Naor, D. (1994). β2-lntegrin dependent aggregate formation between LB T cell lymphoma and spleen cells: assessment of correlation with spleen invasiveness. International immunology, 6(6), 917-924. Isobe, M., Yagita, H., Okumura, K., & Ihara, A. (1992). Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science,255(5048), 1125-1127.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The M18/2 monoclonal antibody specifically binds to mouse CD18, a 95kDA integrin beta 2 glycoprotein. CD18 is expressed on all leukocytes with the highest density by NK and T cells. CD18 forms LFA-1 with CD11a, Mac-1 with CD11b and gp150/95 with CD11c. Through these interactions, CD18 has an important role in cellular adhesion. The M18/2 antibody is reported to stimulate Mac-1 and LFA-1 adhesion to their ligands and block tumor cell metastasis.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Angiogenesis
Format	SAFIRE Purified

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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10212-25-50-datasheet.pdf

10212-25-50-safety-datasheet.pdf