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Anti-Mouse CD289 (TLR9) FITC

ArtNr 31912-50-25
Hersteller BioGems
Menge 25 ug
Kategorie
Typ Antibody
Format FITC
Applikationen FC
Clon M9.D6
Specific against Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG2a
Konjugat/Tag FITC
Citations Kubo, T., Uchida, Y., Watanabe, Y., Abe, M., Nakamura, A., Ono, M., ... & Takai, T. (2009). Augmented TLR9-induced Btk activation in PIR-B-"deficient B-1 cells provokes excessive autoantibody production and autoimmunity. The Journal of experimental medicine, 206(9), 1971-1982.
Fukata, M., Breglio, K., Chen, A., Vamadevan, A. S., Goo, T., Hsu, D., ... & Abreu, M. T. (2008). The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease.The Journal of Immunology, 180(3), 1886-1894.
Miranda-Hernandez, S., Gerlach, N., Fletcher, J. M., Biros, E., Mack, M., Kärner, H., & Baxter, A. G. (2011). Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. The Journal of Immunology, 187(2), 791-804.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Description
The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Storage Temperature
4C
Formulation
Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest
Innate Immunity

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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