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Anti-Mouse CD289 (TLR9) FITC

Anti-Mouse CD289 (TLR9) FITC

Item no.	31912-50-25
Manufacturer	BioGems
Amount	25 ug
Category	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies Neurodegeneration Markers
Type	Antibody
Format	FITC
Applications	FC
Clone	M9.D6
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a
Conjugate/Tag	FITC
Citations	Kubo, T., Uchida, Y., Watanabe, Y., Abe, M., Nakamura, A., Ono, M., ... & Takai, T. (2009). Augmented TLR9-induced Btk activation in PIR-B-"deficient B-1 cells provokes excessive autoantibody production and autoimmunity. The Journal of experimental medicine, 206(9), 1971-1982. Fukata, M., Breglio, K., Chen, A., Vamadevan, A. S., Goo, T., Hsu, D., ... & Abreu, M. T. (2008). The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease.The Journal of Immunology, 180(3), 1886-1894. Miranda-Hernandez, S., Gerlach, N., Fletcher, J. M., Biros, E., Mack, M., Kärner, H., & Baxter, A. G. (2011). Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. The Journal of Immunology, 187(2), 791-804.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

31912-50-25-datasheet.pdf

31912-50-25-safety-datasheet.pdf