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Anti-Mouse IFN gamma SAFIRE Purified

Anti-Mouse IFN gamma SAFIRE Purified

ArtNr	80822-25-500
Hersteller	BioGems
Menge	500 ug
Kategorie	Neuroscience Neuroinflammation Antibodies Flow Cytometry Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Typ	Antibody
Format	SAFIRE (Functional)
Applikationen	FC, IF, IHC, ELISA
Clon	R4-6A2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG1 Kappa
Citations	Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunological reviews, 127(1), 5-24. Cherwinski, H. M., Schumacher, J. H., Brown, K. D., & Mosmann, T. R. (1987). Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. The Journal of experimental medicine, 166(5), 1229-1244. Zhang, Y., Xu, G., Zhang, L., Roberts, A. I., & Shi, Y. (2008). Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-γ. The Journal of Immunology, 181(1), 190-196.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The R4-6A2 monoclonal antibody specifically reacts with mouse interferon gamma (IFN-g), an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN gamma receptors are present in most immune cells, which respond to its signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. Additionally, it stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Innate Immunity, Adaptive Immunity
Format	SAFIRE (Functional)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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80822-25-500-datasheet.pdf

80822-25-500-safety-datasheet.pdf