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Anti-Mouse IFN gamma SAFIRE Purified

Anti-Mouse IFN gamma SAFIRE Purified

Item no.	80822-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Neuroinflammation Antibodies Flow Cytometry Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Type	Antibody
Format	SAFIRE (Functional)
Applications	FC, IF, IHC, ELISA
Clone	R4-6A2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG1 Kappa
Citations	Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunological reviews, 127(1), 5-24. Cherwinski, H. M., Schumacher, J. H., Brown, K. D., & Mosmann, T. R. (1987). Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. The Journal of experimental medicine, 166(5), 1229-1244. Zhang, Y., Xu, G., Zhang, L., Roberts, A. I., & Shi, Y. (2008). Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-γ. The Journal of Immunology, 181(1), 190-196.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The R4-6A2 monoclonal antibody specifically reacts with mouse interferon gamma (IFN-g), an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN gamma receptors are present in most immune cells, which respond to its signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. Additionally, it stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Innate Immunity, Adaptive Immunity
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

80822-25-500-datasheet.pdf

80822-25-500-safety-datasheet.pdf