Anti-Rat CD45R (B220) FITC

ArtNr	07113-50-100
Hersteller	BioGems
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Primary Antibodies By Organ Breast Cancer Progenitor Markers
Typ	Antibody
Format	FITC
Applikationen	FC
Clon	HIS24
Specific against	Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b Kappa
Konjugat/Tag	FITC
Citations	Hermans, M. H. A., Deenen, G. J., De Boer, N., Bo, W., Kroese, F. G. M., & Opstelten, D. (1997). Expression of HIS50 Ag: a rat homologue of mouse heat-stable antigen and human CD24 on B lymphoid cells in the rat. Immunology,90(1), 14-22. Kroese, F. G., Butcher, E. C., Lalor, P. A., Stall, A. M., & Herzenberg, L. A. (1990). The rat B cell system: The anatomical localization of flow cytometry-defined B cell subpopulations. European journal of immunology, 20(7), 1527-1534.Kroese, F. G. M., Opstelten, D., Wubbena, A. S., Deenen, G. J., Aten, J., Schwander, E. H., ... & Nieuwenhuis, P. (1985). Monoclonal antibodies to rat B lymphocyte (sub-) populations. In Microenvironments in the Lymphoid System(pp. 81-89). Springer US.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The HIS24 monoclonal antibody specifically reacts with an isoform of the rat CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells to the exclusion of plasma cells. The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The HIS24 antibody is useful as a marker for the identification of B-cell progenitors.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

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07113-50-100-datasheet.pdf

07113-50-100-safety-datasheet.pdf