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Anti-Rat CD45R (B220) FITC

Anti-Rat CD45R (B220) FITC

Item no.	07113-50-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Primary Antibodies By Organ Breast Cancer Progenitor Markers
Type	Antibody
Format	FITC
Applications	FC
Clone	HIS24
Specific against	Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b Kappa
Conjugate/Tag	FITC
Citations	Hermans, M. H. A., Deenen, G. J., De Boer, N., Bo, W., Kroese, F. G. M., & Opstelten, D. (1997). Expression of HIS50 Ag: a rat homologue of mouse heat-stable antigen and human CD24 on B lymphoid cells in the rat. Immunology,90(1), 14-22. Kroese, F. G., Butcher, E. C., Lalor, P. A., Stall, A. M., & Herzenberg, L. A. (1990). The rat B cell system: The anatomical localization of flow cytometry-defined B cell subpopulations. European journal of immunology, 20(7), 1527-1534.Kroese, F. G. M., Opstelten, D., Wubbena, A. S., Deenen, G. J., Aten, J., Schwander, E. H., ... & Nieuwenhuis, P. (1985). Monoclonal antibodies to rat B lymphocyte (sub-) populations. In Microenvironments in the Lymphoid System(pp. 81-89). Springer US.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The HIS24 monoclonal antibody specifically reacts with an isoform of the rat CD45 glycoprotein. CD45R/B220 is expressed on all the development stages of B cells to the exclusion of plasma cells. The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The HIS24 antibody is useful as a marker for the identification of B-cell progenitors.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

07113-50-100-datasheet.pdf

07113-50-100-safety-datasheet.pdf