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Recombinant Horse Interleukin-1 Receptor Antagonist protein (IL1RN) (Active)

Recombinant Horse Interleukin-1 Receptor Antagonist protein (IL1RN) (Active)

Hersteller	Biomatik
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Obesity
Typ	Proteins Recombinant
Specific against	Equine
Menge	100ug
ArtNr	BM-RPC26545-100ug
Targets	CD121a;;IL6R
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Gene Name	IL1RN
Alternative Names	Interleukin-1 receptor antagonist protein Short name: IL-1RN Short name: IL-1ra Short name: IRAP Alternative name(s): IL1 inhibitor
Uniprot	O18999
Source	E.coli
Expression Region	26-177aa
AA Sequence	HPLGKRPCKM QAFRIWDVNQ KTFYMRNNQL VA GYLQESNT KLQEKIDVVP IEPDALFLGL HGRK LCLACV KSGDEIRFQL EAVNITDLSK NKEENK RFTF IRSNSGPTTS FESAACPGWF LCTAQEAD RP VSLTNKPKES FMVTKFYLQE DQ
Sequence Info	Full Length of Mature Protein
Tag Info	Tag-Free
Theoretical MW	17.4 kDa
Purity	>95% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered PBS, pH 7.4
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by inhibiting IL-1alpha- dependent proliferation of murine D10S cells is less than 3.0 ug/ml, corresponding to a specific activity of ? 333 IU/mg in the presence of 50 pg/ml rHuIL-1alpha.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Function	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Subcellular location	Secreted
Protein Families	IL-1 family

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ug

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Lieferung vsl. bis 27.06.2024

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