Hersteller |
Biomatik
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
Human |
Menge |
100ug |
ArtNr |
BM-RPC20707-100ug |
Targets |
ADRB2 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Gene Name |
ADRB2 |
Alternative Names |
Beta-2 adrenoreceptor Short name: Beta-2 adrenoceptor |
Uniprot |
P07550 |
Source |
in vitro E.coli expression system |
Expression Region |
1-413aa |
AA Sequence |
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVG MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNY FITSLACADLVMGLAVVPFGAAHILMKMWTFGNFW CEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFK YQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYR ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYV PLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNL SQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMG TFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIG YVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAY GNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTE DFVGHQGTVPSDNIDSQGRNCSTNDSLL |
Sequence Info |
Full Length of BC063486 |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
Theoretical MW |
62.5 kDa |
Purity |
>90% as determined by SDS-PAGE. |
Storage Buffer |
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Endotoxin Level |
Not tested |
Biological Activity |
Not tested |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Function |
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Subcellular location |
Cell membrane, Multi-pass membrane protein, Early endosome |
Protein Families |
G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily |
Paythway |
Calciumsignalingpathway |
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