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Recombinant Human Beta-2 adrenergic receptor (ADRB2)

Recombinant Human Beta-2 adrenergic receptor (ADRB2)

Manufacturer	Biomatik
Category	Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Arrhythmias
Type	Proteins Recombinant
Specific against	Human
Amount	100ug
Item no.	BM-RPC20707-100ug
Targets	ADRB2
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene Name	ADRB2
Alternative Names	Beta-2 adrenoreceptor Short name: Beta-2 adrenoceptor
Uniprot	P07550
Source	in vitro E.coli expression system
Expression Region	1-413aa
AA Sequence	MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVG MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNY FITSLACADLVMGLAVVPFGAAHILMKMWTFGNFW CEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFK YQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYR ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYV PLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNL SQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMG TFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIG YVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAY GNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTE DFVGHQGTVPSDNIDSQGRNCSTNDSLL
Sequence Info	Full Length of BC063486
Tag Info	N-terminal 6xHis-SUMO-tagged
Theoretical MW	62.5 kDa
Purity	>90% as determined by SDS-PAGE.
Storage Buffer	Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level	Not tested
Biological Activity	Not tested
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Function	Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Subcellular location	Cell membrane, Multi-pass membrane protein, Early endosome
Protein Families	G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB2 sub-subfamily
Paythway	Calciumsignalingpathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

available

Delivery expected until 6/27/2024