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Recombinant Human Protein Wnt-3a (WNT3A)

ArtNr BM-RPC26102-1mg
Hersteller Biomatik
Menge 1mg
Kategorie
Typ Proteins Recombinant
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Gene Name
WNT3A
Uniprot
P56704
Source
E.coli
Expression Region
19-352aa
AA Sequence
SYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQL RFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNC TTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFA VTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSED IEFGGMVSREFADARENRPDARSAMNRHNNEAGRQ AIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIG DFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYF KVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCN VSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHW CCYVSCQECTRVYDVHTCK
Sequence Info
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged
Theoretical MW
43.5 kDa
Purity
>85% as determined by SDS-PAGE.
Storage Buffer
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level
Not tested
Biological Activity
Not tested
Shipping Condition
Ice packs
Storage
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date
1 year
Restriction
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts.
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Subcellular location
Secreted, extracellular space, extracellular matrix
Protein Families
Wnt family
Tissue Specificity
Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.
Paythway
Hipposignalingpathway

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1mg
Lieferbar: In stock
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