Vergleich

Recombinant Mouse Cell surface hyaluronidase (Tmem2), partial

ArtNr BM-RPC26043-1mg
Hersteller Biomatik
Menge 1mg
Kategorie
Typ Proteins Recombinant
Specific against Mouse (Murine, Mus musculus)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Transmembrane protein 2 (Kiaa1412)
Similar products Transmembrane protein 2 (Kiaa1412)
Lieferbar
Gene Name
Tmem2
Alternative Names
Transmembrane protein 2 (Kiaa1412)
Uniprot
Q5FWI3
Source
Yeast
Expression Region
104-250aa
AA Sequence
SSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEG DLFRLTSDATVDSIVIQDGGLLVFGDDKDGSKNIT LRTRYILIQDGGALHIGAEKCRYRSKATITLYGKS DERESMPIFGKKFIGVEAGGTLELHGAQRTSWTML ARTLHSS
Sequence Info
Partial
Tag Info
N-terminal 10xHis-tagged
Theoretical MW
18.7 kDa
Purity
>85% as determined by SDS-PAGE.
Storage Buffer
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level
Not tested
Biological Activity
Not tested
Shipping Condition
Ice packs
Storage
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date
1 year
Restriction
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate.
Function
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (By similarity). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (By similarity).
Subcellular location
Cell membrane, Single-pass type II membrane protein
Protein Families
TMEM2 family
Tissue Specificity
Widely expressed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1mg
Lieferbar: In stock
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